Metronidazole CAS 443-48-1

CAS:443-48-1

Usoro Molekụla:C6H9N3O3

Ibu Molekụla:171.15

EINECS:207-136-1

Okwu ndị yiri ya:TIMTEC-BB SBB001486; 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole; 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-Methyl-5-nitro-1H-imidazole-1-yl)ethanol; 2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole

Hapụ Ozi Gị

Nkọwa Ngwaahịa

Budata

Akara Ngwaahịa

Kedu ihe bụ Metronidazole CAS 443-48-1?

Metronidazole bụ ntụ ntụ kristal ọcha ma ọ bụ odo odo; Enwere obere isi, nwere ụtọ ilu na obere nnu. Ọ na-agbaze ntakịrị na ethanol, ọ na-agbaze ntakịrị na mmiri ma ọ bụ chloroform, ọ na-agbazekwa ntakịrị na ether. Metronidazole bụ ngwakọta heterocyclic nke nwere nitrogen nwere alkalinity na obere mmiri na-agbaze. Dịka ụkpụrụ prodrug si dị, a na-eme metronidazole ka ọ bụrụ potassium phosphate ester, nke na-eme ka mmiri ya na-agbaze ma nwee ike iji ya dị ka ihe ngwọta ntụtụ.

Nkọwapụta

ihe	Nkọwapụta
Ebe isi mmiri	301.12°C (atụmatụ dị oke njọ)
Njupụta	1.3994 (atụmatụ siri ike)
Ebe agbaze	159-161 Celsius (ọkụ)
pKa	pKa 2.62(H2O,t =25±0.2,
Ọnọdụ nchekwa	2-8°C

Ngwa

Metronidazole nwere mmetụta dị ike nke nje bacteria anaerobic ma a na-eji ya agwọ ọrịa amoebiasis, trichomoniasis, na ọrịa nje anaerobic. A na-ejikwa ya agwọ ọrịa trichomoniasis ikpu ma ejirila ya maka amoebiasis eriri afọ na nke mpụga eriri afọ kemgbe 1970. Ọ dị elu, nsí dị ala, a na-ejikwa ya nke ukwuu. Ọ nwere mmetụta mutagenic na teratogenic na nnwale anụmanụ.