Nnu disodium ATP CAS 987-65-5

CAS:987-65-5

Ịdị ọcha:99%

Usoro Molekụla:C10H17N5NaO13P3

Ibu Molekụla:531.18

EINECS:213-579-1

Oge Nchekwa:afọ 2

Okwu ndị yiri ya:Adenosinetripphosphatedisodium; Adenosinetripphosphate, Disodium Nnu; Adenylpyrophosphoricaciddisodium Nnu; Adenosine-5′-TRIPHOSPHATEHYDRATEDDISODIUM Nnu; Adenosine-5′-TRIPHOSPHATENA2-Nnu; Adenosine-5′-TRIPHOSPHORICACID,DISODIUM; Adenosine-5′-TRIPHOSPHORICACIDDISODIUMNNU; Adenosine5′-TRIPHOSPHORICACIDDISODIUMNNU

Hapụ Ozi Gị

Nkọwa Ngwaahịa

Budata

Akara Ngwaahịa

Kedu ihe bụ ATP disodium nnu CAS 987-65-5?

Nnu disodium ATP bụ metabolite nke adenosine, nucleoside triphosphate nke nwere ọtụtụ ọrụ nke a na-eji dị ka coenzyme maka nnyefe ike n'ime sel. Ọ na-ebufe ike kemịkalụ n'ime sel maka metabolism. A na-eji nnu disodium ATP emepụta analogues nke ribose gbanwere dị ka ligands ndị na-anabata P2Y1.

Nkọwapụta

Ọdịdị	Ntụ ntụ ọcha ma ọ bụ ntụ ntụ ọcha ma ọ bụ ntụ ntụ kristal, hygroscopic.
Nha nke ihe ndị dị ndụ	＞95% gafere site na 80 mesh.
pH	2.5～3.5
Mmiri na-agbaze	Na-agbaze n'ime mmiri; anaghị agbaze na ethanol na ether.
Oder	Enweghị oke
Mmiri dị n'ime ya	6.0%~12.0%
Chloride	≤0.05%
Nnu ígwè	≤0.001%
Ọla dị arọ	≤0.001%
Onye ndu	≤2.0ppm
Arsenic	≤1.0ppm

Ngwa

1. Ojiji nke nyocha ụlọ ọrụ mmepụta ihe na sayensị
(1) Ihe eji achọ mma: etinyere na ngwaahịa nlekọta akpụkpọ ahụ na-egbochi ịka nká, ọ nwere ike ime ka akpụkpọ ahụ dịkwuo mma ma na-egbuke egbuke site n'ịrụ ọrụ metabolism ike sel.
(2) Ihe mgbakwunye nri: eji ya dị ka ihe na-eme ka nri dịkwuo mma n'ihe ọṅụṅụ egwuregwu na nri bara uru iji mejuo ike ngwa ngwa.
2. Ebe ọgwụgwọ ahụike
(1) Ọrịa sistemu obi na akwara obi: eji ya maka nkụda obi, myocarditis, myocardial infarction na cerebral arteriosclerosis, wdg, site na imeziwanye metabolism ike myocardial na ịgbasa akwara obi (ịbawanye ọbara site na ihe dị ka 30%), na-ebelata mgbaàmà ischemia myocardial. Dịka ọmụmaatụ, na ndị ọrịa nwere nnukwu myocardial infarction, ATP disodium nwere ike ime ka oge ọdịda nke ST segment belata ma belata uru kachasị elu nke enzyme spectrum myocardial.
(2) Ọrịa sistemụ akwara: ọgwụgwọ enyemaka nke ihe na-esochi ọbara ọgbụgba n'ụbụrụ, mmebi ụbụrụ na mkpụkọ akwara na-aga n'ihu, site n'itinye aka na mgbochi ọbara-ụbụrụ (ike ịbanye n'ime ihe dị ka 65%), na-akwalite ndozi akpụkpọ ahụ akwara na mmeghari usoro akwara, na imeziwanye ọsọ nke njikọ akwara.
(3) Ọrịa Metabolism: N'ọgwụgwọ ọrịa hepatitis na cirrhosis, ATP disodium nwere ike ime ka ọrụ mitochondrial nke hepatocytes dịkwuo mma, mee ka mmezi hepatocyte dịkwuo ngwa ngwa, ma belata ọkwa ALT na AST; ọ nwekwara mmetụta mmezi enyemaka na nsogbu ndị ọrịa shuga (dịka neuropathy akụkụ).
3. Ebe ndị na-emepe emepe maka ngwa
(1) Sistemụ nnyefe ọgwụ ezubere iche: Enwere ike iji ATP disodium dị ka ihe na-agbanwe ihe, yana liposomes ma ọ bụ nanoparticles, iji nweta nnyefe ọgwụ ezubere iche site na endocytosis nke ndị na-anabata ya na-eme. Dịka ọmụmaatụ, na ọgwụgwọ etuto ahụ, nanomedicines nke ATP gbanwere nwere ike ime ka ọgwụgwọ chemotherapy dịkwuo mma na mkpụrụ ndụ kansa.
(2) Omenala mkpụrụ ndụ na ọgwụ biopharmaceuticals: Dịka akụkụ dị mkpa nke usoro ọdịbendị mkpụrụ ndụ, ATP disodium nwere ike ịkwalite uto na ngosipụta protein nke mkpụrụ ndụ CHO, mkpụrụ ndụ HEK293, wdg, a na-ejikwa ya nke ọma na mmepụta monoclonal antibody.