Metronidazole CAS 443-48-1

CAS:443-48-1

Ụdị molekụla:C6H9N3O3

Ibu Molecular:171.15

EINECS:207-136-1

Ụdị okwu:TIMTEC-BB SBB001486; 1- (2-Hydroxy-1-ethyl) -2-methyl-5-nitroimidazole; 1- (2-hydroxyethyl) -2-methyl-5-nitroimidazole; 1- (beta-Hydroxyethyl) -2-methyl-5-nitroimidazole; 1- (beta-Oxyethyl) -2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol,2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2- (2-Methyl-5-nitro-1H-imidazole-1-yl) ethanol; 2-Methyl-1- (2-hydroxyethyl) -5-nitroimidazole

Hapụ Ozi Gị

Nkọwa ngwaahịa

Budata

Mkpado ngwaahịa

Kedu ihe bụ Metronidazole CAS 443-48-1?

Metronidazole bụ kristal na-acha ọcha ma ọ bụ ubé edo edo ma ọ bụ ntụ ntụ; Enwere ntakịrị isi, nwere uto nnu na ntakịrị nnu. Na-agbaze ntakịrị na ethanol, na-agbaze ntakịrị na mmiri ma ọ bụ chloroform, yana ntakịrị soluble na ether. Metronidazole bụ ọgwụ heterocyclic nwere nitrogen nke nwere alkalinity na obere mmiri solubility. Dị ka ụkpụrụ prodrug si dị, metronidazole na-eme ka ọ bụrụ potassium phosphate ester, nke na-eme ka mmiri dị ike ma nwee ike iji ya mee ihe dị ka ngwọta injection.

Nkọwapụta

Ihe	Nkọwapụta
Ebe esi nri	301.12C (atụmatụ siri ike)
Njupụta	1.3994 (atụmatụ siri ike)
Ebe mgbaze	159-161 Celsius C (ọkụ)
pKa	pKa 2.62 (H2O, t = 25± 0.2,
Ọnọdụ nchekwa	2-8 Celsius C

Ngwa

Metronidazole nwere mmetụta antibacterial siri ike na ọtụtụ nje bacteria anaerobic ma jiri ya na-agwọ amoebiasis, trichomoniasis, na ọrịa nje anaerobic. A na-ejikwa ya na-agwọ trichomoniasis nke ikpu ma jiri ya mee ihe maka amoebiasis nke eriri afọ na extraintestinal kemgbe 1970. Ọrụ ya dị elu, nsị dị ntakịrị, a na-ejikwa ya eme ihe n'ọtụtụ ebe. Nwere mmetụta mutagenic na teratogenic na nnwale anụmanụ.