Madecassic acid nwere CAS 18449-41-7

MF:C30H48O6

Ibu molekụla:504.71

Ọdịdị:Ntụ ntụ

Aha njirimara:(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oicacid;MADECASSICACID;Urs-12-en-28-oicacid,2,3,6,23-tetrahydroxy-,(2.alpha.,3.beta.,4.alpha.,6.beta.)-

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Kedu ihe bụ Madecassic acid na CAS 18449-41-7?

Madecassic acid bụ triterpenoid nke a chọtara na C. asiatica ma nwee ọtụtụ ọrụ dị iche iche na ndụ. Ọ na-egbochi mmepụta nitric oxide (NO), prostaglandin E2 (PGE2; Nkebi Nke 14010), TNF-α, IL-1β, na IL-6 nke LPS kpatara na macrophages RAW 264.7 mgbe ejiri ya na mkpokọta nke 150 μg/ml. Madecassic acid (0.05 na 0.1% na nri) na-ebelata ọkwa plasma nke fibrinogenin na triglycerides, yana ọkwa obi na akụrụ nke ụdị oxygen reactive (ROS), na ụdị òké nke ọrịa shuga nke streptozotocin kpatara (STZ; Nkebi Nke 13104). Ọ na-ebelata uto etuto ahụ na ụdị kansa eriri afọ CT26 n'ụzọ dabere na dose.

Nkọwapụta nke Madecassic acid na CAS 18449-41-7

CAS	18449-41-7
Aha	Asịd Madecassic
Ọdịdị	Ntụ ntụ
Ịdị ọcha	98%
MF	C30H48O6
Ọkwa	Nri $ Ọkwa Ahụike
Ngwugwu	25kgs/akpa, 20tons/20'akpa
Aha akara	Unilong

Iji Madecassic acid mee ihe na CAS 18449-41-7

Madecassic Acid bụ terpenoid nwere ọkpụkpụ ursane nke e kewapụrụ na Centella asiatica. Madecassic Acid na-egosipụta ihe mgbochi mkpali n'ihi mgbochi iNOS, COX-2, TNF-alpha, IL-1beta, na IL-6 site na mbelata nke ọrụ NF-kappaB na mkpụrụ ndụ macrophage RAW 264.7.